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Biomedical Engineering

HIGHLY CITED PAPERS by BU BME AUTHORS 2000-

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma
SS An, TR Bai, JHT Bates, JL Black, RH Brown, V Brusasco, P Chitano, ...
European Respiratory Journal 29 (5), 834-860, 2005

Analysis of changes in reflectance measurements on biological tissues subjected to different probe pressures
R Reif, MS Amorosino, KW Calabro, O A’Amar, SK Singh, IJ Bigio
Journal of biomedical optics 13 (1), 010502-010502-3, 2008

Analysis of optimality in natural and perturbed metabolic networks
D Segre, D Vitkup, GM Church
Proceedings of the National Academy of Sciences 99 (23), 15112-15117, 2002

Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media
Reif, Roberto ; A'Amar, Ousama ; Bigio, Irving J.
Applied Optics, Vol.46 (29), p.7317-7328, 2007

Astrocyte scar formation aids central nervous system axon regeneration
M Anderson, J Burda, Y Ren, Y Ao, TM O’Shea, R Kawaguchi, G Coppola, ...
Nature 532, 195–200,  2016

Bursts of beta oscillation differentiate post-performance activity in the striatum and motor cortex of monkeys performing movement tasks
J Feingold, DJ Gibson, B DePasquale, AM Graybiel
Proceedings of the National Academy of Sciences 112 (44), 13687-13692, 2015

Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
JP Gleghorn, ED Pratt, D Denning, H Liu, NH Bander, ST Tagawa, ...
Lab on a Chip 10 (1), 27-29, 2010

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
McBeath, Rowena ; Pirone, Dana M ; Nelson, Celeste M ; Bhadriraju, Kiran ; Chen, Christopher S
Developmental cell, Vol.6 (4), p.483-495, 2004

Cells lying on a bed of microneedles: an approach to isolate mechanical force
JL Tan, J Tien, DM Pirone, DS Gray, K Bhadriraju, CS Chen
Proceedings of the National Academy of Sciences 100 (4), 1484-1489, 2003

Channel noise in neurons
JA White, JT Rubinstein, AR Kay
Trends in neurosciences 23 (3), 131-137, 2000

The ClusPro web server for protein–protein docking
D Kozakov, DR Hall, B Xia, KA Porter, D Padhorny, C Yueh, D Beglov, ... S Vajda
Nature protocols 12 (2), 255-278, 2017

Clustered dynamics of inhibitory synapses and dendritic spines in the adult neocortex
JL Chen, KL Villa, JW Cha, PTC So, Y Kubota, E Nedivi
Neuron 74 (2), 361-373, 2012

Coherent anti-Stokes Raman scattering microscopy: instrumentation, theory, and applications
JX Cheng, XS Xie
The Journal of Physical Chemistry B 108 (3), 827-840, 2004

Complex oscillatory waves emerging from cortical organoids model early human brain network development
CA Trujillo, R Gao, PD Negraes, J Gu, J Buchanan, S Preissl, A Wang, ...
Cell stem cell 25 (4), 558-569. e7, 2019

Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
NE Fultz, G Bonmassar, K Setsompop, RA Stickgold, BR Rosen, ...
Science 366 (6465), 628-631, 2019

Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex
A Devor, AK Dunn, ML Andermann, I Ulbert, DA Boas, AM Dale
Neuron 39 (2), 353-359, 2003

Directed movement of vascular smooth muscle cells on gradient-compliant hydrogels
JY Wong, A Velasco, P Rajagopalan, Q Pham
Langmuir 19 (5), 1908-1913, 2003

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins 
S Banskota, A Raguram, S Suh, SW Du, JR Davis, EH Choi, X Wang, 
Cell 185 (2), 250-265. e16, 2022 

Engineering microbial biofuel tolerance and export using efflux pumps
MJ Dunlop, ZY Dossani, HL Szmidt, HC Chu, TS Lee, JD Keasling, ...
Molecular systems biology 7 (1), 487, 2011

Force-induced unfolding of fibronectin in the extracellular matrix of living cells
ML Smith, D Gourdon, WC Little, KE Kubow, RA Eguiluz, S Luna-Morris, ...
PLoS biology 5 (10), e268, 2007

A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples
NM Rodriguez, WS Wong, L Liu, R Dewar, CM Klapperich
Lab on a Chip 16 (4), 753-763, 2016

Functional neuroanatomy of biological motion perception in humans
LM Vaina, J Solomon, S Chowdhury, P Sinha, JW Belliveau
Proceedings of the National Academy of Sciences 98 (20), 11656-11661, 2001

Genetic circuit design automation
Nielsen, Alec A. K. ; Der, Bryan S. ; Shin, Jonghyeon ; Vaidyanathan, Prashant ; Paralanov, Vanya ; Strychalski, Elizabeth A. ; Ross, David ; Densmore, Douglas ; Voigt, Christopher A.
Science (American Association for the Advancement of Science), Vol.352 (6281), p.53-53, 2016

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic …
SL James, D Abate, KH Abate, SM Abay, C Abbafati, N Abbasi, ... EO Nsoesie
The Lancet 392 (10159), 1789-1858,  2018

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and …
JD Stanaway, A Afshin, E Gakidou, SS Lim, D Abate, KH Abate, ... EO Nsoesie
The Lancet 392 (10159), 1923-1994,  2018

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1),  1-382, 2021

Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta
Azeloglu, Evren U ; Albro, Michael B ; Thimmappa, Vikrum A ; Ateshian, Gerard A ; Costa, Kevin D
American Journal of Physiology - Heart and Circulatory Physiology, Vol.294 (3), p.1197-1205,  2008

High-performance genetically targetable optical neural silencing by light-driven proton pumps
Chow, X Han, AS Dobry, X Qian, AS Chuong, M Li, MA Henninger, ...
Nature 463 (7277),  98-102,  2010,

In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons
DC Dieterich, JJL Hodas, G Gouzer, IY Shadrin, JT Ngo, A Triller, ...
Nature Neuroscience 13 (7), 897-905, 2010

Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute.  International Human Genome Sequencing Consortium
Nature 409 (6822), 860-921, 2001

Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
Hayrunnisa BolayUwe Reuter, Andrew K. Dunn, Zhihong Huang, David A. Boas, Michael A. Moskowitz
Nature medicine 8 (2), 136-142, 2002

Localized delivery of doxorubicin in vivo from polymer-modified thermosensitive liposomes with MR-guided focused ultrasound-mediated heating
T Ta, E Bartolak-Suki, EJ Park, K Karrobi, NJ McDannold, TM Porter
Journal of controlled release 194, 71-81, 2014

Mechanical behavior in living cells consistent with the tensegrity model
N Wang, K Naruse, D Stamenović, JJ Fredberg, SM Mijailovich, ...
Proceedings of the National Academy of Sciences 98 (14), 7765-7770, 2001

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates
CHJ Choi, L Hao, SP Narayan, E Auyeung, CA Mirkin
Proceedings of the National Academy of Sciences 110 (19), 7625-7630, 2013

Microfluidic synthesis of advanced microparticles for encapsulation and controlled release
WJ Duncanson, T Lin, AR Abate, S Seiffert, RK Shah, DA Weitz
Lab on a Chip 12 (12), 2135-2145, 2012

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis
MH Zaman, LM Trapani, AL Sieminski, D MacKellar, H Gong, RD Kamm, ...
Proceedings of the National Academy of Sciences 103 (29), 10889-10894, 2006

A modular yeast biosensor for low-cost point-of-care pathogen detection
N Ostrov, Miguel Jimenez, S Billerbeck, J Brisbois, J Matragrano, A Ager, ...
Science advances 3 (6), e1603221 124 2017

Noncontact three-dimensional mapping of intracellular hydro-mechanical properties by Brillouin microscopy
G Scarcelli, WJ Polacheck, HT Nia, K Patel, AJ Grodzinsky, RD Kamm, ...
Nature methods 12 (12), 1132, 2015

Objective Detection and Delineation of Oral Neoplasia Using Autofluorescence ImagingAutofluorescence Imaging of Oral Neoplasia
D Roblyer, C Kurachi, V Stepanek, MD Williams, AK El-Naggar, JJ Lee, ...
Cancer prevention research 2 (5), 423-431, 2009

Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming
G Schiebinger, J Shu, M Tabaka, B Cleary, V Subramanian, A Solomon, ...
Cell 176 (4), 928-943. e22, 2019

Overcoming the Cystic Fibrosis Sputum Barrier to Leading Adeno-associated Virus Gene Therapy Vectors
Schuster, Benjamin S ; Kim, Anthony J ; Kays, Joshua C ; Kanzawa, Mia M ; Guggino, William B ; Boyle, Michael P ; Rowe, Steven M ; Muzyczka, Nicholas ; Suk, Jung Soo ; Hanes, Justin
Molecular therapy, Vol.22 (8), p.1484-1493, 2014

Physical traits of cancer
HT Nia, LL Munn, RK Jain
Science 370 (6516), 2020

Quantum Dot-Fluorescent Protein FRET Probes for Sensing Intracellular pH
AM Dennis, WJ Rhee, D Sotto, SN Dublin, G Bao
ACS Nano 6 (4), 2917-2924, 2012

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021

Sensing with photoluminescent semiconductor quantum dots
M Chern, Joshua C Kays, S Bhuckory, AM Dennis
Methods and Applications in Fluorescence 7 (1), 012005 98 2019

Shared and distinct transcriptomic cell types across neocortical areas
B Tasic, Z Yao, LT Graybuck, KA Smith, TN Nguyen, D Bertagnolli, ...
Nature 563 (7729), 72, 2018

Shutting down sensorimotor interference unblocks the networks for stimulus processing: An SMR neurofeedback training study
SE Kober, M Witte, M Stangl, A Väljamäe, C Neuper, G Wood
Clinical Neurophysiology 126 (1), 82-95, 2015

Sorting carbon nanotubes by electronic structure using density differentiation
MS Arnold, AA Green, JF Hulvat, SI Stupp, MC Hersam
Nature nanotechnology 1 (1), 2006, 60-65, 2006

Spectral-temporal receptive fields of nonlinear auditory neurons obtained using natural sounds
FE Theunissen, K Sen, AJ Doupe
Journal of neuroscience 20 (6), 2315-2331, 2000

The structure and function of the endothelial glycocalyx layer
S Weinbaum, JM Tarbell, ER Damiano
Annual Review Biomedical Engineering 9, 121-167, 2007

Structure–function relationships of postnatal tendon development: a parallel to healing
BK Connizzo, SM Yannascoli, LJ Soslowsky
Matrix Biology 32 (2), 106-116, 2013

Synthetic biology: applications come of age
AS Khalil, JJ Collins
Nature Reviews Genetics 11 (5), 367-379, 2010

Temperature treatment of highly porous zirconium-containing metal–organic frameworks extends drug delivery release
MH Teplensky, M Fantham, P Li, TC Wang, JP Mehta, LJ Young, ...
Journal of the American chemical society 139 (22), 7522-7532, 2017

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue 
S Sakadžić, E Roussakis, MA Yaseen, ET Mandeville, VJ Srinivasan,  
Nature methods 7 (9), 755-759, 2010  

Two-photon microscopy in brain tissue: parameters influencing the imaging depth
M Oheim, E Beaurepaire, E Chaigneau, J Mertz, S Charpak
Journal of neuroscience methods 111 (1), 29-37, 2001